Cell-Based Diagnostics in Inflammatory Disease
CellMade discovers new biochemical biomarkers of inflammatory response to measure the effects of new therapies.
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CellInsight™ Cell Culture and Lipidomics Technology
Clinically-relevant insights from primary human cells and stem cells, that help companies to develop better therapeutics and diagnostics for inflammatory diseases.
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CellMade Inflammation Biology Products and Services
Specialist cell-based assays and products that enable target discovery, validation, candidate selection and biomarker discovery in inflammation research.
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Cell-based assays and products based on primary human cells, for inflammation research. Enabling the generation of reliable, clinically-relevant human data in early drug discovery.
Contract research services
Target validation, preclinical efficacy, safety and candidate selection of small molecules or biologics using CellInsight™ human primary cell platform and mass spectrometry bioanalysis.
Novel biomarkers and diagnostics
CellMade is discovering key biochemical inflammatory biomarkers that effectively predict clinical outcomes. Our IP portfolio includes biomarkers of anti-TNFα drug toxicity and inflammatory cytokine modulation.
Our Thinking
Using Lipids To Discover New Drugs
Until now, most researchers have been using single or multi-cytokine activity assays, using ELISA or RT-PCR, or measuring TNFα or TNFα receptor levels to screen for compounds with the potential for anti-infectious or anti-inflammatory applications. You have to do a whole battery of follow-on experiments to find out just what your potential drug candidate might be triggering further downstream, and from there, its potential application. So what if we had a way to precisely monitor and differentiate the downstream effects of TNFα receptor activation, and see these effects within minutes of adding the compound to the screen? Lipid bioanalysis offers a way forward....
Latest News
Launching Inflammatory Cell Biology Services
CellMade, a specialist provider of inflammatory cell biology products and services for biomarker and drug discovery, announces the launch of its new website. Reflecting the company’s leading position in using human cell-based technology to better inform research decisions, the new site features free poster and protocol downloads as well as updated information on the CellInsight™ platform and REACT-lipid™ service. www.cellmade.com looks set to become a primary resource for drug discovery and preclinical researchers working in inflammatory diseases.
