Cell-Based Diagnostics in Inflammatory Disease

Cell-Based Diagnostics in Inflammatory Disease

CellMade discovers new biochemical biomarkers of inflammatory response to measure the effects of new therapies.

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CellInsight™ Cell Culture and Lipidomics Technology

CellInsight™ Cell Culture and Lipidomics Technology

Clinically-relevant insights from primary human cells and stem cells, that help companies to develop better therapeutics and diagnostics for inflammatory diseases.

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CellMade Inflammation Biology Products and Services

CellMade Inflammation Biology Products and Services

Specialist cell-based assays and products that enable target discovery, validation, candidate selection and biomarker discovery in inflammation research.

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Products for inflammation research

Cell-based assays and products based on primary human cells, for inflammation research. Enabling the generation of reliable, clinically-relevant human data in early drug discovery.

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Contract research services

Target validation, preclinical efficacy, safety and candidate selection of small molecules or biologics using CellInsight™ human primary cell platform and mass spectrometry bioanalysis.

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Novel biomarkers and diagnostics

CellMade is discovering key biochemical inflammatory biomarkers that effectively predict clinical outcomes. Our IP portfolio includes biomarkers of anti-TNFα drug toxicity and inflammatory cytokine modulation.

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Our Thinking

Using Lipids To Discover New Drugs

Until now, most researchers have been using single or multi-cytokine activity assays, using ELISA or RT-PCR, or measuring TNFα or TNFα receptor levels to screen for compounds with the potential for anti-infectious or anti-inflammatory applications. You have to do a whole battery of follow-on experiments to find out just what your potential drug candidate might be triggering further downstream, and from there, its potential application. So what if we had a way to precisely monitor and differentiate the downstream effects of TNFα receptor activation, and see these effects within minutes of adding the compound to the screen? Lipid bioanalysis offers a way forward....

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Latest News

Launching Inflammatory Cell Biology Services

CellMade, a specialist provider of inflammatory cell biology products and services for biomarker and drug discovery, announces the launch of its new website. Reflecting the company’s leading position in using human cell-based technology to better inform research decisions, the new site features free poster and protocol downloads as well as updated information on the CellInsight™ platform and REACT-lipid™ service. www.cellmade.com looks set to become a primary resource for drug discovery and preclinical researchers working in inflammatory diseases.

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