Porcine Aortic Smooth Muscle Cells (PAOSMC)
Porcine large artery smooth muscle cells are derived from tunica intima and tunica media of healthy, fibrous plaque-free porcine arteries. They are cryopreserved at first passage (PCASMC at second passage) and can be cultured and propagated at least 16 population doublings (PCASMC at least 14 doublings). Smooth muscle cells have been found in fatty streaks of early arteriosclerosis. Proliferation of the smooth muscle cells is considered a key event in the development of advanced lesions. Porcine smooth muscle cells serve as an alternative for the investigations of cardiac disease and arteriosclerosis. It can be used in co-culture investigation with species-matched porcine artery endothelial cells. |
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 Culturing protocol Product specification Dedicated growth media
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Products
| Name | Description | Size | Reference |
| Cryopreserved PAOSMC, adult | Each ampoule contains >500,000 cryopreserved cells. | 1 Ampoule | CM-2P26-111 |
| Porcine Smooth Muscle Cell Differentiation Medium | Smooth muscle α-actin is expressed in 7-10 days | 250 mL | CM-4P22-054 |
| Porcine Smooth Muscle Cell Growth Medium | Basal Medium & Growth Supplements packaged separately | 500 mL | CM-4P22-041 |
| Subculture Reagent Kit | 100 mL each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution | 3x100 mL | CM-5001-000 |
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