Cell-Based Diagnostics in Inflammatory Disease
CellMade discovers new biochemical biomarkers of inflammatory response to measure the effects of new therapies.
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CellInsight™ Cell Culture and Lipidomics Technology
Clinically-relevant insights from primary human cells and stem cells, that help companies to develop better therapeutics and diagnostics for inflammatory diseases.
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CellMade Inflammation Biology Products and Services
Specialist cell-based assays and products that enable target discovery, validation, candidate selection and biomarker discovery in inflammation research.
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Cell-based assays and products based on primary human cells, for inflammation research. Enabling the generation of reliable, clinically-relevant human data in early drug discovery.
Contract research services
Target validation, preclinical efficacy, safety and candidate selection of small molecules or biologics using CellInsight™ human primary cell platform and mass spectrometry bioanalysis.
Novel biomarkers and diagnostics
CellMade is discovering key biochemical inflammatory biomarkers that effectively predict clinical outcomes. Our IP portfolio includes biomarkers of anti-TNFα drug toxicity and inflammatory cytokine modulation.
Our Thinking
Lipids As Biomarkers in Immune Mediated Inflammatory Diseases
Recent literature underlines the potential of lipid biomarkers for use in immune mediated inflammatory diseases. Here's a summary of the evidence for lipids as key modulators in innate as well as adaptive immunity. Here, we show how changes in lipid profiles can be used in the drug discovery and preclinical setting to monitor pro- and anti-inflammatory effects of new compounds, for early safety and efficacy screening. Because lipids are so accessible from peripheral tissues, discovery of lipid profiles associated with changes in immune-mediated inflammatory processes could be useful in the clinic.
Latest News
Launching Inflammatory Cell Biology Services
CellMade, a specialist provider of inflammatory cell biology products and services for biomarker and drug discovery, announces the launch of its new website. Reflecting the company’s leading position in using human cell-based technology to better inform research decisions, the new site features free poster and protocol downloads as well as updated information on the CellInsight™ platform and REACT-lipid™ service. www.cellmade.com looks set to become a primary resource for drug discovery and preclinical researchers working in inflammatory diseases.
